Rheumatoid Arthritis Research Today is a free monthly online journal that collates and summarizes the latest research about Rheumatoid Arthritis, including details on treatment, symptoms, causes, medication.

Acute erythroleukemia in a rheumatoid arthritis patient during low-dose methotrexate therapy.

Choi BR, Ahn MJ, Lee WS, Kim TH, Bae SC, Jun JB

Hospital for Rheumatic Diseases, Hanyang University, 17 Haengdang-Dong, Sungdong-Gu, Seoul 133-792, Korea.

Acute leukemia is uncommonly seen with rheumatoid arthritis during or following treatment with low-dose methotrexate, a safe and effective treatment for the arthritic condition. We describe here a 68-year-old woman with rheumatoid arthritis who developed acute erythroleukemia during low-dose methotrexate therapy (total dose 1702.5 mg). This may be the first such case reported in the literature.

Published 12 May 2005 in Rheumatol Int, 25(4): 311-3.
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